SafeDose Updates Clinical Content to Reflect October 2025 PALS Guidelines

by | Dec 8, 2025

Ensuring clinicians have immediate access to the most current pediatric emergency medication dosing and protocols

Southborough, MA, December 8, 2025 – SafeDose, a pioneer in the safe, simple, and standardized delivery of pediatric medication, today announced the completion of a scheduled update to its clinical content library to incorporate all relevant changes introduced in the October 2025 update to the Pediatric Advanced Life Support (PALS) guidelines. The updated content is now available to all SafeDose users across the platform.

Maintaining accurate, current pediatric medication dosing information and clinical administration instructions is the core mission of the SafeDose clinical team. When national standards are updated, clinicians need to know that the tools they rely upon at the point of care reflect those changes without delay.

PALS guidelines, developed and maintained by the American Heart Association (AHA), establish the evidence-based standards for pediatric emergency care, including resuscitation protocols, weight-based medication dosing, and treatment algorithms for life-threatening conditions in children. Updates to these guidelines reflect the most current clinical research and are considered authoritative across emergency departments, pediatric units, and pre-hospital settings.

The SafeDose clinical team conducted a thorough review of the October 2025 PALS update and has incorporated all applicable changes into the platform’s pediatric formulary, code sheets, and clinical administration guidance. This ensures that the weight-based dosing calculations, drug preparation instructions, and resuscitation protocols available within SafeDose are fully consistent with the updated standards.

More than 80% of children receive their initial emergency care at community and regional hospitals, where pediatric emergencies may be infrequent and dedicated pediatric specialists may not always be available. In these settings, having point-of-care access to accurate, guideline-current dosing information is critical to patient safety and outcomes. SafeDose is trusted by thousands of clinicians across 500+ hospitals to provide that information quickly and reliably.

SafeDose customers can access the updated clinical content immediately through their existing platform login. For more information about SafeDose or to schedule a demonstration, please visit www.safedoseinc.com.

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About SafeDose, Inc.
SafeDose, Inc. is dedicated to developing a simple, safe, and effective international standard for acute drug administration and furthering the goal of pediatric care readiness. SafeDose® is used by thousands of clinicians daily, furthering the company’s mission to provide needed critical information to those administering acute care — helping them improve treatment, save lives, and simplify their jobs. To learn more about joining the SafeDose medication safety movement, please visit the company website at www.safedoseinc.com.